A jean on the x chromosome explains the higher incidence of Alzheimer's disease in women

A scientific study has found a genetic explanation for the higher rate of Alzheimer's disease in women compared to men due to the important role of sex chromosomes.Alzheimer's form A

Researchers have identified a gene on the female X chromosome called KDM6A that activates the inflammatory response in the brain.This research was done in experiments on modified mice.Deleting the gene was able to improve symptoms and other neurological problems, and the results were greater in women.

A study published in the magazine Science translational Medicine found that women who have two X chromosomes double the harmful inflamation "dose" compared with people who have one X chromosome.The results also showed the possibility of using the drug metformin - approved to treat diabetes - to stabilize the genius and its inflammatory pathways, still followed by widespread prescriptions during the year.

Dr. Rhonda Voskohl, who led the research team, explained that the data not only characterizes the symptoms of Alzheimer's disease and multiple sclerosis in women, but could also open the door to understanding “brain fog” in two-thirds of healthy postmenopausal women, suggesting the development of gender-specific drug approaches.

Although there is still no cure for dementia, early diagnosis allows for personalized treatment plans, medications and treatments that delay the onset of the disease.The study confirms the need for a gender perspective with the potential to benefit from existing medications such as Metrine.

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